Phenotypes associated with this allele

• Allele Symbol: Sorbs2^{tm1.1(KOMP)Mbp}
• Allele Name: targeted mutation 1.1, Mouse Biology Program, UC Davis
• Allele ID: MGI:5494474
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sorbs2^tm1.1(KOMP)Mbp/Sorbs2^tm1.1(KOMP)Mbp	C57BL/6N-Sorbs2^tm1.1(KOMP)Mbp/J	MGI:5631577

Genotype
MGI:5631577

hm1

• Allelic Composition: Sorbs2^{tm1.1(KOMP)Mbp}/Sorbs2^{tm1.1(KOMP)Mbp}
• Genetic Background: C57BL/6N-Sorbs2^{tm1.1(KOMP)Mbp}/J
• Cell Lines: DEPD00505_6_B03

Data Sources

IMPC Data for Sorbs2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

IMPC - JAX

increased heart rate ( J:211773 )

IMPC - JAX

shortened PR interval ( J:211773 )

♂

IMPC - JAX

shortened PQ interval ( J:211773 )

IMPC - JAX

shortened ST segment ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

decreased circulating cholesterol level ( J:211773 )

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - JAX

decreased circulating free fatty acids level ( J:211773 )

♂

IMPC - JAX

increased circulating sodium level ( J:211773 )

♂

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - JAX