Phenotypes associated with this allele

• Allele Symbol: Rfc1^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5495286
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rfc1^tm1b(KOMP)Mbp/Rfc1^tm1b(KOMP)Mbp	B6N(Cg)-Rfc1^tm1b(KOMP)Mbp/J	MGI:5763854
ht2	Rfc1^tm1b(KOMP)Mbp/Rfc1^+	B6N(Cg)-Rfc1^tm1b(KOMP)Mbp/J	MGI:5763853

Genotype
MGI:5763854

hm1

• Allelic Composition: Rfc1^{tm1b(KOMP)Mbp}/Rfc1^{tm1b(KOMP)Mbp}
• Genetic Background: B6N(Cg)-Rfc1^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00519_1_F03

Data Sources

IMPC Data for Rfc1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5763853

ht2

• Allelic Composition: Rfc1^{tm1b(KOMP)Mbp}/Rfc1⁺
• Genetic Background: B6N(Cg)-Rfc1^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00519_1_F03

Data Sources

IMPC Data for Rfc1

embryo

abnormal embryo turning ( J:211773 )

IMPC - JAX

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

IMPC - JAX

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

decreased circulating free fatty acids level ( J:211773 )

IMPC - JAX