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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fabp6tm1Lbal
targeted mutation 1, Luis B Agellon
MGI:5495685
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fabp6tm1Lbal/Fabp6tm1Lbal B6.129-Fabp6tm1Lbal MGI:5495754


Genotype
MGI:5495754
hm1
Allelic
Composition
Fabp6tm1Lbal/Fabp6tm1Lbal
Genetic
Background
B6.129-Fabp6tm1Lbal
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fabp6tm1Lbal mutation (0 available); any Fabp6 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in male, but not female, mice
• in male, but not female, mice
• increased fecal bile acid excretion in female, but not male, mice
• male mice exhibit impaired movement of bile acids out of the small intestine compared with wild-type mice
• in the plasma of female, but not male, mice
• administered bile acids are retained in the small intestine and distal gut sacs of male, but not female, mice
• decreased cholesterol ester concentration in female, but not male, mice

liver/biliary system
• decreased cholesterol ester concentration in female, but not male, mice
• in female mice
• however, the difference was not significant in male mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory