About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fabp6tm1Lbal
targeted mutation 1, Luis B Agellon
MGI:5495685
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fabp6tm1Lbal/Fabp6tm1Lbal B6.129-Fabp6tm1Lbal MGI:5495754


Genotype
MGI:5495754
hm1
Allelic
Composition
Fabp6tm1Lbal/Fabp6tm1Lbal
Genetic
Background
B6.129-Fabp6tm1Lbal
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fabp6tm1Lbal mutation (0 available); any Fabp6 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in male, but not female, mice
• in male, but not female, mice
• increased fecal bile acid excretion in female, but not male, mice
• male mice exhibit impaired movement of bile acids out of the small intestine compared with wild-type mice
• in the plasma of female, but not male, mice
• administered bile acids are retained in the small intestine and distal gut sacs of male, but not female, mice
• decreased cholesterol ester concentration in female, but not male, mice

liver/biliary system
• decreased cholesterol ester concentration in female, but not male, mice
• in female mice
• however, the difference was not significant in male mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory