Analysis Tools
mortality/aging
| N |
• doxycycline-treated mice exhibit normal postnatal survival
|
|
• mice begin to die at E10.5 and are all dead by E13.5
• however, treatment with doxycycline rescues embryonic lethality
|
nervous system
|
• severity of defects depends on doxycycline administration, especially during P2 to P11
|
|
• at 12 weeks in mice from dams treated with doxycycline for a day at E0.5
|
|
• at 12 weeks in mice from dams treated with doxycycline for a day at E0.5
|
|
• at 12 weeks in mice from dams treated with doxycycline for a day at E0.5
|
|
• at 12 weeks in mice from dams treated with doxycycline for a day at E0.5
|
limbs/digits/tail
syndactyly
(
J:196015
)
|
• to different degrees in mice from dams treated with doxycycline for a day at E0.5
• failure of separation of soft tissue between adjacent fingers
|
growth/size/body
| N |
• doxycycline-treated mice exhibit normal body weight
|
