Phenotypes associated with this allele

• Allele Symbol: Pkd2^tm1Sia
• Allele Name: targeted mutation 1, Shinichi Aizawa
• Allele ID: MGI:5496378
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pkd2^tm1Sia/Pkd2^tm1Sia	Not Specified	MGI:5496380

Genotype
MGI:5496380

hm1

• Allelic Composition: Pkd2^tm1Sia/Pkd2^tm1Sia
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:195164 )

• mice die between E12.5 and birth

embryonic lethality during organogenesis, incomplete penetrance ( J:195164 )

• mice die between E12.5 and birth

embryo

abnormal primitive node morphology ( J:195164 )

• calcium signal frequency in the node is reduced and signals are more symmetric compared to in wild-type mice