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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm2Iaai
targeted mutation 2, Iannis Aifantis
MGI:5496402
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm2Iaai/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0 		involves: 129S/SvEv * C57BL/6 MGI:5496426


Genotype
MGI:5496426
cn1
Allelic
Composition		 Gt(ROSA)26Sortm2Iaai/Gt(ROSA)26Sor+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2Iaai mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Ndor1Tg(UBC-cre/ERT2)1Ejb mutation (6 available); any Ndor1 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal bone marrow cell physiology ( J:196407 )
• total bone marrow cells transplanted in lethally irradiated recipients and treated with tamoxifen induce aggressive T-cell acute lymphoblastic leukemia (T-ALL) resulting in death unlike control cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory