About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp277tm1Aiwa
targeted mutation 1, Atsushi Iwama
MGI:5496522
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Zfp277tm1Aiwa/Zfp277tm1Aiwa involves: 129S1/Sv * 129X1/SvJ MGI:5496526


Genotype
MGI:5496526
hm1
Allelic
Composition		 Zfp277tm1Aiwa/Zfp277tm1Aiwa
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp277tm1Aiwa mutation (0 available); any Zfp277 mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
early cellular replicative senescence ( J:198334 )
• in mouse embryonic fibroblasts at passage 6
• however, replication is rescued by HPV-16 E6 expression




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory