All Phenotypes Rhof<tm1.2Tac> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rhof^tm1.2Tac
targeted mutation 1.2, Taconic
MGI:5496692

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rhof^tm1.2Tac/Rhof^tm1.2Tac	involves: C57BL/6	MGI:5496712

Allelic Composition	Rhof^tm1.2Tac/Rhof^tm1.2Tac
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhof^tm1.2Tac mutation (0 available); any Rhof mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:195926 )

N	• platelets exhibit normal filopodia formation and spreading, integrin activation, aggregation, secretion of dense granules and adherence and filopodia formation under high shear

thrombocytopenia ( J:195926 )

• macrothrombocytopenia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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