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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Card11M2Btlr
mutation 2, Bruce Beutler
MGI:5497995
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Card11M2Btlr/Card11M2Btlr involves: C57BL/6J MGI:5498083


Genotype
MGI:5498083
hm1
Allelic
Composition		 Card11M2Btlr/Card11M2Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Card11M2Btlr mutation (1 available); any Card11 mutation (59 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgM level ( J:198555 )
• low T-independent IgM responses 5 days after immunization with NP-Ficoll
• however, mice exhibit normal T-dependent IgG responses 14 days after immunization with a recombinant SFV vector encoding the model antigen

hematopoietic system
decreased IgM level ( J:198555 )
• low T-independent IgM responses 5 days after immunization with NP-Ficoll
• however, mice exhibit normal T-dependent IgG responses 14 days after immunization with a recombinant SFV vector encoding the model antigen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory