Phenotypes associated with this allele

• Allele Symbol: Eif4g2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5498138
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eif4g2^tm1b(KOMP)Wtsi/Eif4g2^tm1b(KOMP)Wtsi	C57BL/6N-Eif4g2^tm1b(KOMP)Wtsi/J	MGI:5757038
ht2	Eif4g2^tm1b(KOMP)Wtsi/Eif4g2^+	C57BL/6N-Eif4g2^tm1b(KOMP)Wtsi/J	MGI:5757037

Genotype
MGI:5757038

hm1

• Allelic Composition: Eif4g2^{tm1b(KOMP)Wtsi}/Eif4g2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Eif4g2^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0322_4_E10

Data Sources

IMPC Data for Eif4g2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5757037

ht2

• Allelic Composition: Eif4g2^{tm1b(KOMP)Wtsi}/Eif4g2⁺
• Genetic Background: C57BL/6N-Eif4g2^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0322_4_E10

Data Sources

IMPC Data for Eif4g2

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - JAX

decreased circulating glucose level ( J:211773 )

♀

IMPC - JAX

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - JAX

impaired glucose tolerance ( J:211773 )

♂

IMPC - JAX

decreased circulating chloride level ( J:211773 )

IMPC - JAX

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - JAX

decreased bone mineral content ( J:211773 )

♀

IMPC - JAX

decreased bone mineral density ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - JAX