Phenotypes associated with this allele

• Allele Symbol: Sdha^{tm2b(KOMP)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5498775
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sdha^tm2b(KOMP)Wtsi/Sdha^tm2b(KOMP)Wtsi	C57BL/6N-Sdha^tm2b(KOMP)Wtsi/J	MGI:5631521
ht2	Sdha^tm2b(KOMP)Wtsi/Sdha^+	C57BL/6N-Sdha^tm2b(KOMP)Wtsi/J	MGI:5631520

Genotype
MGI:5631521

hm1

• Allelic Composition: Sdha^{tm2b(KOMP)Wtsi}/Sdha^{tm2b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Sdha^{tm2b(KOMP)Wtsi}/J
• Cell Lines: EPD0670_1_C11

Data Sources

IMPC Data for Sdha

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5631520

ht2

• Allelic Composition: Sdha^{tm2b(KOMP)Wtsi}/Sdha⁺
• Genetic Background: C57BL/6N-Sdha^{tm2b(KOMP)Wtsi}/J
• Cell Lines: EPD0670_1_C11

Data Sources

IMPC Data for Sdha

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - JAX

decreased thigmotaxis ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

increased circulating free fatty acids level ( J:211773 )

♂

IMPC - JAX

increased circulating sodium level ( J:211773 )

♂

IMPC - JAX