Phenotypes associated with this allele

• Allele Symbol: Nos3^tm3.1Plh
• Allele Name: targeted mutation 3.1, Paul L Huang
• Allele ID: MGI:5499172
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nos3^tm3.1Plh/Nos3^tm3.1Plh	involves: 129S4/SvJae * C57BL/6	MGI:5499175

Genotype
MGI:5499175

hm1

• Allelic Composition: Nos3^tm3.1Plh/Nos3^tm3.1Plh
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating glucose level ( J:198075 )

• in fasting mice fed a high fat diet

increased circulating insulin level ( J:198075 )

• in non-fasting mice fed standard chow or a high fat diet

• in fasting mice fed a high fat diet

improved glucose tolerance ( J:198075 )

adipose tissue

decreased white fat cell size ( J:198075 )

• compared to in Nos3^tm2.1Plh homozygotes