mortality/aging
|
• mice die between E11.5 and E13.5
|
embryo
|
• some embryos have abnormal morphology at E8.5
|
|
• at E9.5 and E10.5
|
cardiovascular system
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• cardiac malformations at E9.5
|
craniofacial
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• at E9.5 and E10.5
|
growth/size/body
|
• at E9.5 and E10.5
|
skeleton
|
• at E9.5 and E10.5
|