Phenotypes associated with this allele

• Allele Symbol: Tg(Lck-Akt2*)#Test
• Allele Name: transgene insertion, Joseph R Testa
• Allele ID: MGI:5500790
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Lck-Akt2*)#Test/0	Not Specified	MGI:5513096

Genotype
MGI:5513096

tg1

• Allelic Composition: Tg(Lck-Akt2*)#Test/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:153923 , J:154583 )

• median survival is 75-140 days of age (J:153923)

neoplasm

increased lymphoma incidence ( J:154583 )

increased T cell derived lymphoma incidence ( J:153923 )

• 95-100% of mice develop aggressive thymic lymphomas

• thymic lymphomas develop chromosome alterations

endocrine/exocrine glands

increased T cell derived lymphoma incidence ( J:153923 )

• 95-100% of mice develop aggressive thymic lymphomas

• thymic lymphomas develop chromosome alterations

immune system

increased T cell derived lymphoma incidence ( J:153923 )

• 95-100% of mice develop aggressive thymic lymphomas

• thymic lymphomas develop chromosome alterations

hematopoietic system

increased T cell derived lymphoma incidence ( J:153923 )

• 95-100% of mice develop aggressive thymic lymphomas

• thymic lymphomas develop chromosome alterations