All Phenotypes Del(19Poll-Fbxw4)4Fsp MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Del(19Poll-Fbxw4)4Fsp
deletion, Chr 19, Francois Spitz 4
MGI:5501313

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Del(19Poll-Fbxw4)4Fsp/+ Fgf8^tm1.4Mrt/Fgf8⁺	involves: 129P2/OlaHsd * 129S1/Sv	MGI:5501452
cx2	Del(19Poll-Fbxw4)4Fsp/Del(19Poll-Fgf8)5Fsp	involves: 129P2/OlaHsd * 129S1/Sv	MGI:5501453

Allelic Composition	Del(19Poll-Fbxw4)4Fsp/+ Fgf8^tm1.4Mrt/Fgf8⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(19Poll-Fbxw4)4Fsp mutation (0 available); any Del(19Poll-Fbxw4)4Fsp mutation (0 available)
Fgf8^tm1.4Mrt mutation (0 available); any Fgf8 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:196292 )

• despite expected Mendelian ratios at E9.5 to E10.5, fewer than expected mice are present at E18.5

nervous system

abnormal brain morphology ( J:196292 )

• at E9.5 to E10.5

abnormal brain development ( J:196292 )

• deletion of midbrain/cerebellum structures

absent olfactory bulb ( J:196292 )

limbs/digits/tail

absent forelimb ( J:196292 )

absent hindlimb ( J:196292 )

short limbs ( J:196292 )

• at E9.5 to E10.5

renal/urinary system

absent kidney ( J:196292 )

craniofacial

abnormal craniofacial morphology ( J:196292 )

• strong

embryo

embryonic growth retardation ( J:196292 )

• at E9.5 to E10.5

growth/size/body

embryonic growth retardation ( J:196292 )

• at E9.5 to E10.5

Allelic Composition	Del(19Poll-Fbxw4)4Fsp/Del(19Poll-Fgf8)5Fsp
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryonic growth retardation ( J:196292 )

• at E9.5 to E10.5

growth/size/body

embryonic growth retardation ( J:196292 )

• at E9.5 to E10.5

limbs/digits/tail

short limbs ( J:196292 )

• at E9.5 to E10.5

nervous system

abnormal brain morphology ( J:196292 )

• at E9.5 to E10.5

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