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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sykm1Btlr
mutation 1, Bruce Beutler
MGI:5502198
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sykm1Btlr/Sykm1Btlr involves: C57BL/6J MGI:5502217


Genotype
MGI:5502217
hm1
Allelic
Composition		 Sykm1Btlr/Sykm1Btlr
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sykm1Btlr mutation (1 available); any Syk mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased tumor necrosis factor secretion ( J:199281 )
• from macrophages stimulated with agonists LPS, MALP2 or R848

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory