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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ggntm1Dpj
targeted mutation 1, Duangporn Jamsai
MGI:5503309
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ggntm1Dpj/Ggntm1Dpj B6.129-Ggntm1Dpj MGI:5503310
ht2
 		Ggntm1Dpj/Ggn+ B6.129-Ggntm1Dpj MGI:5503311


Genotype
MGI:5503310
hm1
Allelic
Composition		 Ggntm1Dpj/Ggntm1Dpj
Genetic
Background		 B6.129-Ggntm1Dpj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ggntm1Dpj mutation (2 available); any Ggn mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:199404 )
• mice die between the first mitotic division and implanatation




Genotype
MGI:5503311
ht2
Allelic
Composition		 Ggntm1Dpj/Ggn+
Genetic
Background		 B6.129-Ggntm1Dpj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ggntm1Dpj mutation (2 available); any Ggn mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal double-strand DNA break repair ( J:199404 )
• increased unrepaired double-strand breaks in pachytene spermatocytes

homeostasis/metabolism
abnormal double-strand DNA break repair ( J:199404 )
• increased unrepaired double-strand breaks in pachytene spermatocytes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory