All Phenotypes Fbxl21<tm1Kei> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fbxl21^tm1Kei
targeted mutation 1, Keiichi I Nakayama
MGI:5503967

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxl21^tm1Kei/Fbxl21^tm1Kei	B6.129P2-Fbxl21^tm1Kei	MGI:5503969
cx2	Fbxl21^tm1Kei/Fbxl21^tm1Kei Fbxl3^tm1Kei/Fbxl3^tm1Kei	B6.129P2-Fbxl21^tm1Kei Fbxl3^tm1Kei	MGI:5503970

Allelic Composition	Fbxl21^tm1Kei/Fbxl21^tm1Kei
Genetic Background	B6.129P2-Fbxl21^tm1Kei

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl21^tm1Kei mutation (1 available); any Fbxl21 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal circadian behavior ( J:196293 )

• mice fail to exhibit two peak of activity bouts unlike wild-type mice

• however, mice exhibit normal activity in constant darkness and onset of activity in 12L:12D cycle

Allelic Composition	Fbxl21^tm1Kei/Fbxl21^tm1Kei Fbxl3^tm1Kei/Fbxl3^tm1Kei
Genetic Background	B6.129P2-Fbxl21^tm1Kei Fbxl3^tm1Kei

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxl21^tm1Kei mutation (1 available); any Fbxl21 mutation (26 available)
Fbxl3^tm1Kei mutation (1 available); any Fbxl3 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal circadian behavior ( J:196293 )

• unstable behavior rhythm in constant darkness

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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