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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map2k1tm1Bacc
targeted mutation 1, Manuela Baccarini
MGI:5504398
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Map2k1tm1Bacc/Map2k1tm1.1Bacc
Meox2tm1(cre)Sor/Meox2+ 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 MGI:5504404
cn2
 		Map2k1tm1Bacc/Map2k1tm1.1Bacc
Edil3Tg(Sox2-cre)1Amc/Edil3+ 		involves: 129P2/OlaHsd * C57BL/6 * CBA MGI:5504406
cn3
 		Map2k1tm1Bacc/Map2k1tm1.1Bacc
Tg(Nes-cre)1Kln/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:5504405


Genotype
MGI:5504404
cn1
Allelic
Composition		 Map2k1tm1Bacc/Map2k1tm1.1Bacc
Meox2tm1(cre)Sor/Meox2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2k1tm1.1Bacc mutation (0 available); any Map2k1 mutation (94 available)
Map2k1tm1Bacc mutation (2 available); any Map2k1 mutation (94 available)
Meox2tm1(cre)Sor mutation (3 available); any Meox2 mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:199705 )
N
• embryonic lethality observed in Map2k1tm1.1Bacc homozygotes is rescued




Genotype
MGI:5504406
cn2
Allelic
Composition		 Map2k1tm1Bacc/Map2k1tm1.1Bacc
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
Map2k1tm1.1Bacc mutation (0 available); any Map2k1 mutation (94 available)
Map2k1tm1Bacc mutation (2 available); any Map2k1 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:199705 )
• mice do not exhibit any obvious phenotypes




Genotype
MGI:5504405
cn3
Allelic
Composition		 Map2k1tm1Bacc/Map2k1tm1.1Bacc
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2k1tm1.1Bacc mutation (0 available); any Map2k1 mutation (94 available)
Map2k1tm1Bacc mutation (2 available); any Map2k1 mutation (94 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
postnatal growth retardation ( J:199705 )
• slight after P20

nervous system
nervous system phenotype ( J:199705 )
N
• mice exhibit normal gross brain, central and peripheral nervous system anatomy




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory