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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Shox2tm3.1(cre)Ypc
targeted mutation 3.1, YiPing Chen
MGI:5504508
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Shox2tm3.1(cre)Ypc/Shox2tm4.1Ypc involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 MGI:5504521
cn2
Shox2tm1Ddu/Shox2tm3.1(cre)Ypc involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 MGI:5504523


Genotype
MGI:5504521
ht1
Allelic
Composition
Shox2tm3.1(cre)Ypc/Shox2tm4.1Ypc
Genetic
Background
involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shox2tm3.1(cre)Ypc mutation (0 available); any Shox2 mutation (20 available)
Shox2tm4.1Ypc mutation (0 available); any Shox2 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• lethality is observed beginning at E11.5, increasing as development progresses

cardiovascular system
• the sinoatrial node (SAN) is hypoplastic at E11.5 similar to Shox2tm1Ypc homozygous embryos

muscle
• the sinoatrial node (SAN) is hypoplastic at E11.5 similar to Shox2tm1Ypc homozygous embryos




Genotype
MGI:5504523
cn2
Allelic
Composition
Shox2tm1Ddu/Shox2tm3.1(cre)Ypc
Genetic
Background
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Shox2tm1Ddu mutation (1 available); any Shox2 mutation (20 available)
Shox2tm3.1(cre)Ypc mutation (0 available); any Shox2 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• lethality is observed beginning at E11.5, increasing as development progresses

cardiovascular system
• the sinoatrial node (SAN) is hypoplastic at E11.5 similar to Shox2tm1Ypc homozygous embryos

muscle
• the sinoatrial node (SAN) is hypoplastic at E11.5 similar to Shox2tm1Ypc homozygous embryos





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory