Phenotypes associated with this allele

• Allele Symbol: Grin2a^tm1.1Nhk
• Allele Name: targeted mutation 1.1, Noboru H Komiyama
• Allele ID: MGI:5505778
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grin2a^tm1.1Nhk/Grin2a^tm1.1Nhk	involves: 129P2/OlaHsd * C57BL/6J	MGI:5505863

Genotype
MGI:5505863

hm1

• Allelic Composition: Grin2a^tm1.1Nhk/Grin2a^tm1.1Nhk
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired contextual conditioning behavior ( J:197485 )

• mice exhibit reduced freezing during testing compared with wild-type mice

decreased anxiety-related response ( J:197485 )

• in an open field, mice travel more distance and take less time to enter the inner zone compared with wild-type mice

impaired coordination ( J:197485 )

nervous system

nervous system phenotype ( J:197485 )

N • mice exhibit normal long term potentiation following theta burst stimulation and theta burst stimulation