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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(EGR3-WGA)1Tmj
transgene insertion 1, Thomas M Jessel
MGI:5505904
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Etv1tm1Tmj/Etv1tm2Tmj
Tg(EGR3-WGA)1Tmj/0 		involves: 129S1/Sv MGI:5506525


Genotype
MGI:5506525
cx1
Allelic
Composition		 Etv1tm1Tmj/Etv1tm2Tmj
Tg(EGR3-WGA)1Tmj/0
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv1tm1Tmj mutation (0 available); any Etv1 mutation (44 available)
Etv1tm2Tmj mutation (0 available); any Etv1 mutation (44 available)
Tg(EGR3-WGA)1Tmj mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
decreased muscle spindle number ( J:197913 )
• mutants exhibit loss of about 65% of WGA-positive muscle spindles relative to controls

nervous system
decreased muscle spindle number ( J:197913 )
• mutants exhibit loss of about 65% of WGA-positive muscle spindles relative to controls
decreased sensory neuron number ( J:197913 )
• number of wheat germ agglutinin-positive (WGA) proprioceptive sensory neurons in L2 and L5 DRG is significantly reduced (to 20% of control)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory