Phenotypes associated with this allele

• Allele Symbol: Del(2Hoxd1-Hoxd9)63Ddu
• Allele Name: deletion, Chr 2, Denis Duboule 63
• Allele ID: MGI:5508523
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Del(2Hoxd1-Hoxd9)63Ddu/+	involves: C57BL/6 * CBA	MGI:5508535

Genotype
MGI:5508535

ht1

• Allelic Composition: Del(2Hoxd1-Hoxd9)63Ddu/+
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:199759 )

• only half of mice survive to adulthood

• Background Sensitivity: lethality increases after serial backcrosses to C57BL/6

postnatal lethality, incomplete penetrance ( J:199759 )

behavior/neurological

abnormal sexual interaction ( J:199759 )

♀ • female mice chase male mice regardless of genotype, lift them and and bite their genitals

♀ • female mice continue to pursue male mice after copulation unlike control mice

♀ • however, no aggression is observed otherwise

increased mating frequency ( J:199759 )

♀ • in some female mice

craniofacial

malocclusion ( J:199759 )

short snout ( J:199759 )

growth/size/body

malocclusion ( J:199759 )

short snout ( J:199759 )

postnatal growth retardation ( J:199759 )

skeleton

malocclusion ( J:199759 )