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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Kittm5.1Bsm
targeted mutation 5.1, Peter Besmer
MGI:5510143
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Kittm5.1Bsm/Kit+ involves: 129S1/Sv * C57BL/6J * FVB/N MGI:5510144


Genotype
MGI:5510144
ht1
Allelic
Composition
Kittm5.1Bsm/Kit+
Genetic
Background
involves: 129S1/Sv * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kittm5.1Bsm mutation (0 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Cecal gastrointestinal stromal tumor and gastric/colonic interstatial cell of Cajal hyperplasia in Kittm5.1Bsm/Kit+ and Kittm4.1Bsm/Kit+ mice

mortality/aging

neoplasm
• mice develop cecal tumors that are larger than in Kittm4.1Bsm heterozygotes
• compared to in Kittm4.1Bsm heterozygotes

digestive/alimentary system
• less pronounced in the stomach and colon than in Kittm4.1Bsm heterozygotes
• mice develop cecal tumors that are larger than in Kittm4.1Bsm heterozygotes

hematopoietic system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory