Phenotypes associated with this allele

• Allele Symbol: Pax6^Aey80
• Allele Name: abnormality of the eye 80
• Allele ID: MGI:5511011
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax6^Aey80/Pax6^Aey80	C3HeB/FeJ-Pax6^Aey80	MGI:5511020
ht2	Pax6^Aey80/Pax6^+	C3HeB/FeJ-Pax6^Aey80	MGI:5511023

Genotype
MGI:5511020

hm1

• Allelic Composition: Pax6^Aey80/Pax6^Aey80
• Genetic Background: C3HeB/FeJ-Pax6^Aey80

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:196657 )

• no homozygotes are identified after birth

vision/eye

anophthalmia ( J:196657 )

• homozygous embryos lack eyes

Genotype
MGI:5511023

ht2

• Allelic Composition: Pax6^Aey80/Pax6⁺
• Genetic Background: C3HeB/FeJ-Pax6^Aey80

vision/eye

vision/eye phenotype ( J:196657 )

N • the adult lens and cornea are clear

N • no lens-cornea adhesions as seen in embryos

abnormal eye morphology ( J:196657 )

corneal-lenticular stalk ( J:196657 )

• fusion between the lens and cornea in E15.5 embryos

• synechia between the lens and cornea

small lens ( J:196657 )

• slightly smaller than controls

• significantly reduced lens thickness

abnormal eye size ( J:196657 )

• axial length of the eye is reduced

microphthalmia ( J:196657 )

• small eyes

blindness ( J:196657 )

• as a result of strain background