Phenotypes associated with this allele

• Allele Symbol: Atp6v1b2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5513747
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp6v1b2^tm1b(KOMP)Wtsi/Atp6v1b2^tm1b(KOMP)Wtsi	C57BL/6N-Atp6v1b2^tm1b(KOMP)Wtsi/Tcp	MGI:5756764
ht2	Atp6v1b2^tm1b(KOMP)Wtsi/Atp6v1b2^+	C57BL/6N-Atp6v1b2^tm1b(KOMP)Wtsi/Tcp	MGI:5756763

Genotype
MGI:5756764

hm1

• Allelic Composition: Atp6v1b2^{tm1b(KOMP)Wtsi}/Atp6v1b2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Atp6v1b2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0205_4_C02

Data Sources

IMPC Data for Atp6v1b2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5756763

ht2

• Allelic Composition: Atp6v1b2^{tm1b(KOMP)Wtsi}/Atp6v1b2⁺
• Genetic Background: C57BL/6N-Atp6v1b2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0205_4_C02

Data Sources

IMPC Data for Atp6v1b2

endocrine/exocrine glands

small adrenal glands ( J:211773 )

IMPC - TCP

hematopoietic system

decreased hemoglobin content ( J:211773 )

♂

IMPC - TCP

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - TCP

decreased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - TCP

decreased mean corpuscular volume ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - TCP

immune system

small lymph nodes ( J:211773 )

♂

IMPC - TCP