Phenotypes associated with this allele

• Allele Symbol: Chd1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5513752
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chd1^tm1b(KOMP)Wtsi/Chd1^tm1b(KOMP)Wtsi	C57BL/6N-Chd1^tm1b(KOMP)Wtsi/Tcp	MGI:5756866
ht2	Chd1^tm1b(KOMP)Wtsi/Chd1^+	C57BL/6N-Chd1^tm1b(KOMP)Wtsi/Tcp	MGI:5756865

Genotype
MGI:5756866

hm1

• Allelic Composition: Chd1^{tm1b(KOMP)Wtsi}/Chd1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Chd1^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0806_4_B08

Data Sources

IMPC Data for Chd1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5756865

ht2

• Allelic Composition: Chd1^{tm1b(KOMP)Wtsi}/Chd1⁺
• Genetic Background: C57BL/6N-Chd1^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0806_4_B08

Data Sources

IMPC Data for Chd1

behavior/neurological

increased grip strength ( J:211773 )

♂

IMPC - TCP

craniofacial

abnormal tooth morphology ( J:211773 )

♂

IMPC - TCP

abnormal maxilla morphology ( J:211773 )

♂

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal tooth morphology ( J:211773 )

♂

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - TCP

decreased red blood cell distribution width ( J:211773 )

IMPC - TCP

skeleton

abnormal tooth morphology ( J:211773 )

♂

IMPC - TCP

abnormal maxilla morphology ( J:211773 )

♂

IMPC - TCP

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - TCP

anophthalmia ( J:211773 )

♂

IMPC - TCP