Phenotypes associated with this allele

• Allele Symbol: Coa5^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5513757
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Coa5^tm1b(KOMP)Wtsi/Coa5^tm1b(KOMP)Wtsi	C57BL/6N-Coa5^tm1b(KOMP)Wtsi/Tcp	MGI:5756891
ht2	Coa5^tm1b(KOMP)Wtsi/Coa5^+	C57BL/6N-Coa5^tm1b(KOMP)Wtsi/Tcp	MGI:5756890

Genotype
MGI:5756891

hm1

• Allelic Composition: Coa5^{tm1b(KOMP)Wtsi}/Coa5^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Coa5^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0362_6_A09

Data Sources

IMPC Data for Coa5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5756890

ht2

• Allelic Composition: Coa5^{tm1b(KOMP)Wtsi}/Coa5⁺
• Genetic Background: C57BL/6N-Coa5^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0362_6_A09

Data Sources

IMPC Data for Coa5

behavior/neurological

decreased locomotor activity ( J:211773 )

♂

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

small adrenal glands ( J:211773 )

♂

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

IMPC - TCP

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - TCP