Phenotypes associated with this allele

• Allele Symbol: Cox19^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5513759
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cox19^tm1b(EUCOMM)Hmgu/Cox19^tm1b(EUCOMM)Hmgu	C57BL/6N-Cox19^tm1b(EUCOMM)Hmgu/Tcp	MGI:5756908
ht2	Cox19^tm1b(EUCOMM)Hmgu/Cox19^+	C57BL/6N-Cox19^tm1b(EUCOMM)Hmgu/Tcp	MGI:5756907

Genotype
MGI:5756908

hm1

• Allelic Composition: Cox19^{tm1b(EUCOMM)Hmgu}/Cox19^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Cox19^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0679_7_C08

Data Sources

IMPC Data for Cox19

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5756907

ht2

• Allelic Composition: Cox19^{tm1b(EUCOMM)Hmgu}/Cox19⁺
• Genetic Background: C57BL/6N-Cox19^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0679_7_C08

Data Sources

IMPC Data for Cox19

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

IMPC - TCP

increased circulating phosphate level ( J:211773 )

♂

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP