Phenotypes associated with this allele

• Allele Symbol: Eprs1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5513771
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Eprs1^tm1b(EUCOMM)Hmgu/Eprs1^tm1b(EUCOMM)Hmgu	C57BL/6N-Eprs1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757056
ht2	Eprs1^tm1b(EUCOMM)Hmgu/Eprs1^+	C57BL/6N-Eprs1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5767654

Genotype
MGI:5757056

hm1

• Allelic Composition: Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0704_5_B03

Data Sources

IMPC Data for Eprs1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5767654

ht2

• Allelic Composition: Eprs1^{tm1b(EUCOMM)Hmgu}/Eprs1⁺
• Genetic Background: C57BL/6N-Eprs1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0704_5_B03

Data Sources

IMPC Data for Eprs1

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

IMPC - TCP

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - TCP

respiratory system

abnormal lung morphology ( J:211773 )

♂

IMPC - TCP