Phenotypes associated with this allele

• Allele Symbol: Ggnbp2^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5513782
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ggnbp2^tm1b(KOMP)Wtsi/Ggnbp2^tm1b(KOMP)Wtsi	C57BL/6N-Ggnbp2^tm1b(KOMP)Wtsi/Tcp	MGI:5757170
ht2	Ggnbp2^tm1b(KOMP)Wtsi/Ggnbp2^+	C57BL/6N-Ggnbp2^tm1b(KOMP)Wtsi/Tcp	MGI:5757169

Genotype
MGI:5757170

hm1

• Allelic Composition: Ggnbp2^{tm1b(KOMP)Wtsi}/Ggnbp2^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Ggnbp2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0553_4_A06

Data Sources

IMPC Data for Ggnbp2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

vision/eye

anophthalmia ( J:211773 )

♀

IMPC - TCP

Genotype
MGI:5757169

ht2

• Allelic Composition: Ggnbp2^{tm1b(KOMP)Wtsi}/Ggnbp2⁺
• Genetic Background: C57BL/6N-Ggnbp2^{tm1b(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0553_4_A06

Data Sources

IMPC Data for Ggnbp2

cardiovascular system

shortened QRS complex duration ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - TCP

decreased circulating total protein level ( J:211773 )

♀

IMPC - TCP

edema ( J:211773 )

IMPC - TCP