Phenotypes associated with this allele

• Allele Symbol: Plekhm1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5513810
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plekhm1^tm1b(EUCOMM)Hmgu/Plekhm1^tm1b(EUCOMM)Hmgu	C57BL/6N-Plekhm1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757528

Genotype
MGI:5757528

hm1

• Allelic Composition: Plekhm1^{tm1b(EUCOMM)Hmgu}/Plekhm1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Plekhm1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0506_2_A05

Data Sources

IMPC Data for Plekhm1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - TCP

growth/size/body

polycystic kidney ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - TCP

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - TCP

nervous system

abnormal optic disk morphology ( J:211773 )

♂

IMPC - TCP

decreased prepulse inhibition ( J:211773 )

IMPC - TCP

renal/urinary system

polycystic kidney ( J:211773 )

♀

IMPC - TCP

skeleton

short tibia ( J:211773 )

♀

IMPC - TCP

abnormal vertebrae morphology ( J:211773 )

♂

IMPC - TCP

increased bone mineral content ( J:211773 )

♂

IMPC - TCP

increased bone mineral density ( J:211773 )

♂

IMPC - TCP

vision/eye

abnormal optic disk morphology ( J:211773 )

♂

IMPC - TCP