Phenotypes associated with this allele

• Allele Symbol: Mtf1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5515625
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mtf1^tm1b(KOMP)Wtsi/Mtf1^tm1b(KOMP)Wtsi	C57BL/6N-Mtf1^tm1b(KOMP)Wtsi/J	MGI:5757382
ht2	Mtf1^tm1b(KOMP)Wtsi/Mtf1^+	C57BL/6N-Mtf1^tm1b(KOMP)Wtsi/J	MGI:5757381

Genotype
MGI:5757382

hm1

• Allelic Composition: Mtf1^{tm1b(KOMP)Wtsi}/Mtf1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Mtf1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0025_1_G12

Data Sources

IMPC Data for Mtf1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

♀

IMPC - JAX

embryo

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal forebrain morphology ( J:211773 )

IMPC - JAX

vision/eye

microphthalmia ( J:211773 )

♂

IMPC - JAX

anophthalmia ( J:211773 )

♂

IMPC - JAX

Genotype
MGI:5757381

ht2

• Allelic Composition: Mtf1^{tm1b(KOMP)Wtsi}/Mtf1⁺
• Genetic Background: C57BL/6N-Mtf1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0025_1_G12

Data Sources

IMPC Data for Mtf1

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX

increased circulating potassium level ( J:211773 )

IMPC - JAX

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - JAX