Phenotypes associated with this allele

• Allele Symbol: 4933427D14Rik^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5515778
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	4933427D14Rik^tm1.1(KOMP)Vlcg/4933427D14Rik^tm1.1(KOMP)Vlcg	B6N(Cg)-4933427D14Rik^tm1.1(KOMP)Vlcg/J	MGI:5763823

Genotype
MGI:5763823

hm1

• Allelic Composition: 4933427D14Rik^{tm1.1(KOMP)Vlcg}/4933427D14Rik^{tm1.1(KOMP)Vlcg}
• Genetic Background: B6N(Cg)-4933427D14Rik^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 18550A-G4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

4933427D14Rik^{tm1.1(KOMP)Vlcg}/4933427D14Rik^{tm1.1(KOMP)Vlcg} mice exhibit embryonic lethality embryos recovered at E7.5 but not at E9.5. Embryos exhibit abnormal embryo turning and growth retardation at E8.5.

mortality/aging

embryonic lethality prior to organogenesis, complete penetrance ( J:279207 )

• homozygous embryos are recovered in expected ratios at E7.5 but found dead at E9.5

embryo

abnormal embryo turning ( J:279207 )

• embryos fail to properly turn

embryonic growth retardation ( J:279207 )

• embryos are significantly delayed at E8.5

• however, most morphological features typical of E7.5 and E8.5 are present

decreased embryo size ( J:279207 )

• embryos appear slightly smaller than controls at E7.5

growth/size/body

embryonic growth retardation ( J:279207 )

• embryos are significantly delayed at E8.5

• however, most morphological features typical of E7.5 and E8.5 are present

decreased embryo size ( J:279207 )

• embryos appear slightly smaller than controls at E7.5