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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prnp-ATXN3*148Q)NES.24Olri
transgene insertion NES.24, Olaf Riess
MGI:5516458
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Prnp-ATXN3*148Q)NES.24Olri/0 involves: C57BL/6N MGI:5516460


Genotype
MGI:5516460
tg1
Allelic
Composition		 Tg(Prnp-ATXN3*148Q)NES.24Olri/0
Genetic
Background		 involves: C57BL/6N
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
short stride length ( J:122993 )
• distance between each step is reduced at 11 months of age and mutants walk on tiptoe, however behavioral symptoms are mild compared to transgenics with the nuclear localization signal

nervous system
nervous system phenotype ( J:122993 )
N
• mutants have very low number of inclusion bodies and normal Purkinje cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory