Phenotypes associated with this allele

• Allele Symbol: Npr1^tm1.1Rsha
• Allele Name: targeted mutation 1.1, Rameshwar K Sharma
• Allele ID: MGI:5516490
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npr1^tm1.1Rsha/Npr1^tm1.1Rsha	involves: C57BL/6	MGI:5516491
ht2	Npr1^tm1.1Rsha/Npr1^+	involves: C57BL/6	MGI:5516492

Genotype
MGI:5516491

hm1

• Allelic Composition: Npr1^tm1.1Rsha/Npr1^tm1.1Rsha
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased heart weight ( J:201932 )

cardiac hypertrophy ( J:201932 )

increased mean systemic arterial blood pressure ( J:201932 )

increased systemic arterial systolic blood pressure ( J:201932 )

homeostasis/metabolism

increased circulating aldosterone level ( J:201932 )

growth/size/body

increased heart weight ( J:201932 )

cardiac hypertrophy ( J:201932 )

Genotype
MGI:5516492

ht2

• Allelic Composition: Npr1^tm1.1Rsha/Npr1⁺
• Genetic Background: involves: C57BL/6

cardiovascular system

increased heart weight ( J:201932 )

cardiac hypertrophy ( J:201932 )

increased mean systemic arterial blood pressure ( J:201932 )

increased systemic arterial systolic blood pressure ( J:201932 )

homeostasis/metabolism

increased circulating aldosterone level ( J:201932 )

growth/size/body

increased heart weight ( J:201932 )

cardiac hypertrophy ( J:201932 )