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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pcsk9m1Bms
mutation 1, Bristol Myers Squibb
MGI:5516591
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pcsk9m1Bms/Pcsk9m1Bms B6.Cg-Pcsk9m1Bms MGI:5516592
ht2
 		Pcsk9m1Bms/Pcsk9+ B6.Cg-Pcsk9m1Bms MGI:5516593


Genotype
MGI:5516592
hm1
Allelic
Composition		 Pcsk9m1Bms/Pcsk9m1Bms
Genetic
Background		 B6.Cg-Pcsk9m1Bms
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcsk9m1Bms mutation (0 available); any Pcsk9 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased bile salt level ( J:200728 )
• 1.5- to 2-fold increase in fecal bile acids without atorvastatin treatment




Genotype
MGI:5516593
ht2
Allelic
Composition		 Pcsk9m1Bms/Pcsk9+
Genetic
Background		 B6.Cg-Pcsk9m1Bms
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcsk9m1Bms mutation (0 available); any Pcsk9 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory