About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gng13tm1Liqh
targeted mutation 1, Liquan Huang
MGI:5517361
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gng13tm1Liqh/Gng13tm1Liqh
Omptm4(cre)Mom/Omp+ 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 MGI:5517417


Genotype
MGI:5517417
cn1
Allelic
Composition		 Gng13tm1Liqh/Gng13tm1Liqh
Omptm4(cre)Mom/Omp+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gng13tm1Liqh mutation (0 available); any Gng13 mutation (8 available)
Omptm4(cre)Mom mutation (2 available); any Omp mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:197147 )
• although mice are grossly normal, those born into litters of 7 or more display compromised survival

taste/olfaction
abnormal olfactory system morphology ( J:197147 )
• olfactory glomerular structures and axon bundles are somewhat altered
abnormal olfactory sensory neuron physiology ( J:197147 )
• 15 odorants tested including the pheromones 2-heptanone, DMP, and TMT
• "electro-olfactogram" response to all odorants is significantly diminished
• TEA response becomes positive rather than the typical negative
impaired olfaction ( J:197147 )
• mice deprived of food for 1 day take 518 seconds to find a buried food pellet scented with peanut butter whereas controls take 26-27 seconds
• all mice find the pellet rapidly when placed on the surface of the bedding

nervous system
abnormal olfactory sensory neuron physiology ( J:197147 )
• 15 odorants tested including the pheromones 2-heptanone, DMP, and TMT
• "electro-olfactogram" response to all odorants is significantly diminished
• TEA response becomes positive rather than the typical negative

respiratory system
abnormal olfactory sensory neuron physiology ( J:197147 )
• 15 odorants tested including the pheromones 2-heptanone, DMP, and TMT
• "electro-olfactogram" response to all odorants is significantly diminished
• TEA response becomes positive rather than the typical negative




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory