All Phenotypes Lmnb1<tm1.2Sgy> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lmnb1^tm1.2Sgy
targeted mutation 1.2, Stephen G Young
MGI:5517590

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lmnb1^tm1.2Sgy/Lmnb1^tm1.2Sgy	involves: 129P2/OlaHsd * FVB/N	MGI:5517695

Allelic Composition	Lmnb1^tm1.2Sgy/Lmnb1^tm1.2Sgy
Genetic Background	involves: 129P2/OlaHsd * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmnb1^tm1.2Sgy mutation (0 available); any Lmnb1 mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal neuron morphology ( J:197315 )

• dumb bell shaped rather than round nuclei in neurons migrating out of neurospheres in culture

• asymmetric distribution of nuclear envelop proteins in neurons migrating out of neurospheres in culture

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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