All Phenotypes Pygo2<tm1.1Kba> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pygo2^tm1.1Kba
targeted mutation 1.1, Konrad Basler
MGI:5518423

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pygo2^tm1.1Kba/Pygo2^tm1.1Kba	involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NTac	MGI:5518433
cx2	Pygo1^tm1.1Kba/Pygo1^tm1.1Kba Pygo2^tm1.1Kba/Pygo2^tm1.1Kba	involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NTac	MGI:5518434

Allelic Composition	Pygo2^tm1.1Kba/Pygo2^tm1.1Kba
Genetic Background	involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pygo2^tm1.1Kba mutation (0 available); any Pygo2 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:198562 )

N	• mice are born in expected Mendelian ratios

reproductive system

reproductive system phenotype ( J:198562 )

N	• female mice exhibit normal reproduction and are able to properly feed their young

Allelic Composition	Pygo1^tm1.1Kba/Pygo1^tm1.1Kba Pygo2^tm1.1Kba/Pygo2^tm1.1Kba
Genetic Background	involves: 129S6/SvEvTac * C57BL/6N * C57BL/6NTac

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pygo1^tm1.1Kba mutation (0 available); any Pygo1 mutation (21 available)
Pygo2^tm1.1Kba mutation (0 available); any Pygo2 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

oligozoospermia ( J:198562 )

• severe depletion of mature sperm cells in the lumen of most seminiferous tubules without a change in proliferation or apoptosis in the testis

abnormal spermatid morphology ( J:198562 )

• impaired nuclear condensation of elongating spermatids