About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(Gli2)Jmao
targeted mutation 1, Junhao Mao
MGI:5518625
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+ 		involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ MGI:5518632
cn2
 		Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Nkx3-2tm1(cre)Wez/Nkx3-2+ 		involves: 129S7/SvEvBrd MGI:5518631


Genotype
MGI:5518632
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Smotm2Amc/Smotm2Amc
Nkx3-2tm1(cre)Wez/Nkx3-2+
Genetic
Background		 involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Gli2)Jmao mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Nkx3-2tm1(cre)Wez mutation (0 available); any Nkx3-2 mutation (21 available)
Smotm2Amc mutation (1 available); any Smo mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Gli2 expression, but not Gli3 de-repression, rescues intestinal phenotypes in Smotm2Amc/Smotm2Amc Nkx3-2tm1(cre)Wez/Nkx3-2+ embryos

digestive/alimentary system
digestive/alimentary phenotype ( J:199664 )
N
• intestinal development is rescued




Genotype
MGI:5518631
cn2
Allelic
Composition		 Gt(ROSA)26Sortm1(Gli2)Jmao/Gt(ROSA)26Sor+
Nkx3-2tm1(cre)Wez/Nkx3-2+
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Gli2)Jmao mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Nkx3-2tm1(cre)Wez mutation (0 available); any Nkx3-2 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Gli2 expression, but not Gli3 de-repression, rescues intestinal phenotypes in Smotm2Amc/Smotm2Amc Nkx3-2tm1(cre)Wez/Nkx3-2+ embryos

digestive/alimentary system
digestive/alimentary phenotype ( J:199664 )
N
• mice exhibit normal intestinal development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory