Phenotypes associated with this allele

• Allele Symbol: Mbnl3^tm1.1Sws
• Allele Name: targeted mutation 1.1, Maurice S Swanson
• Allele ID: MGI:5518844
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mbnl3^tm1.1Sws/Mbnl3^tm1.1Sws	involves: BALB/c * C57BL/6 * C57BL/6J	MGI:5518852
ot2	Mbnl3^tm1.1Sws/Y	involves: BALB/c * C57BL/6 * C57BL/6J	MGI:5518853

Genotype
MGI:5518852

hm1

• Allelic Composition: Mbnl3^tm1.1Sws/Mbnl3^tm1.1Sws
• Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

decreased skeletal muscle fiber size ( J:199127 )

♀ • decreased cross-sectional area in mice treated with notexin

decreased skeletal muscle fiber number ( J:199127 )

♀ • in mice treated with notexin

impaired skeletal muscle regeneration ( J:199127 )

♀ • progressive impairment in older mice injected with notexin

behavior/neurological

decreased grip strength ( J:199127 )

♀ • in mice treated with notexin

Genotype
MGI:5518853

ot2

• Allelic Composition: Mbnl3^tm1.1Sws/Y
• Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J

muscle

decreased skeletal muscle fiber size ( J:199127 )

♂ • decreased cross-sectional area in mice treated with notexin

decreased skeletal muscle fiber number ( J:199127 )

♂ • in mice treated with notexin

impaired skeletal muscle regeneration ( J:199127 )

♂ • progressive impairment in older mice injected with notexin

behavior/neurological

decreased grip strength ( J:199127 )

♂ • in mice treated with notexin