All Phenotypes + MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

+
wild type
MGI:5519897

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Scs/+	(C3H/He-Scs/GrsrJ x C57BL/6J)F1	MGI:5519899
ht2	Scs/+	(C3H/He-Scs/GrsrJ x CAST/EiJ)F1	MGI:5646119
ht3	Scs/+	C3H/He-Scs/GrsrJ	MGI:5646117

Allelic Composition	Scs/+
Genetic Background	(C3H/He-Scs/GrsrJ x C57BL/6J)F1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scs mutation (1 available); any Scs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Abnormal axial skeleton morphology and short tail in Scs/+ mouse

skeleton

abnormal axial skeleton morphology ( J:202091 )

abnormal rib morphology ( J:202091 )

• fused or bifurcated ribs can be found

rib bifurcation ( J:202091 )

rib fusion ( J:202091 )

abnormal vertebral column morphology ( J:202091 )

• compressed, shortened, sometimes crooked or kinked spine and tail

abnormal intervertebral disk morphology ( J:202091 )

• intervertebral discs are sometimes missing or herniated

absent intervertebral disk ( J:202091 )

prolapsed intervertebral disk ( J:202091 )

abnormal vertebrae morphology ( J:202091 )

• cervical, thoracic, lumbar and sacral vertebrae can be compressed, misshapen, and irregularly aligned and misaligned vertebrae can be fused resulting in a crooked spine or tail kink

vertebral compression ( J:202091 )

vertebral fusion ( J:202091 )

short vertebral column ( J:202091 )

• the vertebral defects result in a compressed, shortened body length

abnormal skeleton development ( J:202091 )

limbs/digits/tail

short tail ( J:202091 )

Allelic Composition	Scs/+
Genetic Background	(C3H/He-Scs/GrsrJ x CAST/EiJ)F1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scs mutation (1 available); any Scs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short tail ( J:202091 )

• somewhat stumpy and sometimes kinked tail approximately three quarters of an inch in length

skeleton

abnormal axial skeleton morphology ( J:202091 )

• shortened, compacted body due to abnormal axial skeleton development

abnormal skeleton development ( J:202091 )

Allelic Composition	Scs/+
Genetic Background	C3H/He-Scs/GrsrJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scs mutation (1 available); any Scs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal axial skeleton morphology ( J:202091 )

• shortened, compacted body due to abnormal axial skeleton development

abnormal skeleton development ( J:202091 )

limbs/digits/tail

short tail ( J:202091 )

• somewhat stumpy and sometimes kinked tail approximately three quarters of an inch in length

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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