Phenotypes associated with this allele

• Allele Symbol: Rab34^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5520180
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rab34^tm1b(EUCOMM)Hmgu/Rab34^tm1b(EUCOMM)Hmgu	C57BL/6N-Rab34^tm1b(EUCOMM)Hmgu/J	MGI:5757596
ht2	Rab34^tm1b(EUCOMM)Hmgu/Rab34^+	C57BL/6N-Rab34^tm1b(EUCOMM)Hmgu/J	MGI:5759419

Genotype
MGI:5757596

hm1

• Allelic Composition: Rab34^{tm1b(EUCOMM)Hmgu}/Rab34^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Rab34^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0666_1_D01

Data Sources

IMPC Data for Rab34

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - JAX

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

facial cleft ( J:211773 )

IMPC - JAX

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - JAX

embryo

abnormal limb bud morphology ( J:211773 )

♀

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

facial cleft ( J:211773 )

IMPC - JAX

abnormal body wall morphology ( J:211773 )

IMPC - JAX

homeostasis/metabolism

edema ( J:211773 )

IMPC - JAX

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - JAX

abnormal limb bud morphology ( J:211773 )

♀

IMPC - JAX

polydactyly ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

vision/eye

anophthalmia ( J:211773 )

IMPC - JAX

Genotype
MGI:5759419

ht2

• Allelic Composition: Rab34^{tm1b(EUCOMM)Hmgu}/Rab34⁺
• Genetic Background: C57BL/6N-Rab34^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0666_1_D01

Data Sources

IMPC Data for Rab34

cardiovascular system

increased heart weight ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

IMPC - JAX