Phenotypes associated with this allele

• Allele Symbol: Prkci^{tm2.1(Prkcz)Ltg}
• Allele Name: targeted mutation 2.1, Michael Leitges
• Allele ID: MGI:5520925
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkci^tm2.1(Prkcz)Ltg/Prkci^tm2.1(Prkcz)Ltg	involves: 129P2/OlaHsd * NMRI	MGI:5520952

Genotype
MGI:5520952

hm1

• Allelic Composition: Prkci^{tm2.1(Prkcz)Ltg}/Prkci^{tm2.1(Prkcz)Ltg}
• Genetic Background: involves: 129P2/OlaHsd * NMRI

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Growth retardation of E9.5 Prkci^{tm2.1(Prkcz)Ltg}/Prkci^{tm2.1(Prkcz)Ltg} embryos

mortality/aging

lethality during fetal growth through weaning, complete penetrance ( J:202124 )

• no mice are present at P21

embryonic lethality, incomplete penetrance ( J:202124 )

• fewer than expected mice are present at E7.5 and E9.5

embryonic lethality during organogenesis, incomplete penetrance ( J:202124 )

• fewer than expected mice are present at E9.5

• however, complete lethality by E10.5 observed in null embryos is rescued

growth/size/body

embryonic growth retardation ( J:202124 )

• at E9.5

embryo

embryonic growth retardation ( J:202124 )

• at E9.5