nervous system
• regional reduction of SLC17A7 and global reduction in GAD2 puncta indicating a reduction in synapse density
• significant reduction of asymmetric synapse density in stratum radiatum andof symmetric synapse density in stratum pyramidale
• reduction in both excitatory and inhibitory synapse density
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• regional reduction of SLC17A7 and global reduction in GAD2 puncta indicating a reduction in synapse density
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• significant reduction of symmetric synapse density in the CA1 stratum pyramidale
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• significant reduction of asymmetric synapse density in the CA1 stratum radiatum
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• significant enhancement in fEPSP responses in hippocampal slices at the higher end of the stimulation range
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• reduction in mEPSC frequency but not amplitude
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• reduction in mIPSC frequency but not amplitude, increase in interevent interval
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