All Phenotypes Piwil2<tm2.2Doca> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Piwil2^tm2.2Doca
targeted mutation 2.2, Donal O'Carroll
MGI:5521293

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Piwil2^tm2.2Doca/Piwil2^tm2.2Doca	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ * C57BL/6J	MGI:5521300

Allelic Composition	Piwil2^tm2.2Doca/Piwil2^tm2.2Doca
Genetic Background	involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piwil2^tm2.2Doca mutation (1 available); any Piwil2 mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal spermatocyte morphology ( J:199259 )

• early spermatocytes

abnormal spermatogonia morphology ( J:199259 )

cellular

abnormal spermatocyte morphology ( J:199259 )

• early spermatocytes

abnormal spermatogonia morphology ( J:199259 )

abnormal cell physiology ( J:199259 )

• L1 expression is deregulated in late zygotene or early pachytene

• however, L1 repression is normal in spermatogonia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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