Phenotypes associated with this allele

• Allele Symbol: Slc9b2^tm1.1Dgfu
• Allele Name: targeted mutation 1.1, Daniel G Fuster
• Allele ID: MGI:5521370
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc9b2^tm1.1Dgfu/Slc9b2^tm1.1Dgfu	B6.129-Slc9b2^tm1.1Dgfu	MGI:5521379
hm2	Slc9b2^tm1.1Dgfu/Slc9b2^tm1.1Dgfu	involves: 129 * C57BL/6	MGI:5521376
ht3	Slc9b2^tm1.1Dgfu/Slc9b2^+	involves: 129 * C57BL/6	MGI:5521378

Genotype
MGI:5521379

hm1

• Allelic Composition: Slc9b2^tm1.1Dgfu/Slc9b2^tm1.1Dgfu
• Genetic Background: B6.129-Slc9b2^tm1.1Dgfu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

increased circulating glucose level ( J:197386 )

• increase in serum glucose after i.p. glucose load is greater than for controls

endocrine/exocrine glands

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

Genotype
MGI:5521376

hm2

• Allelic Composition: Slc9b2^tm1.1Dgfu/Slc9b2^tm1.1Dgfu
• Genetic Background: involves: 129 * C57BL/6

homeostasis/metabolism

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

increased circulating glucose level ( J:197386 )

• increase in serum glucose after i.p. glucose load is greater than for controls

decreased circulating insulin level ( J:197386 )

endocrine/exocrine glands

decreased insulin secretion ( J:197386 )

• insulin secretion of isolated islets induced with 20mM glucose is greatly reduced

Genotype
MGI:5521378

ht3

• Allelic Composition: Slc9b2^tm1.1Dgfu/Slc9b2⁺
• Genetic Background: involves: 129 * C57BL/6

homeostasis/metabolism

increased circulating glucose level ( J:197386 )

• increase in serum glucose after i.p. glucose load is greater than for controls