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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata1tm1.1Yen
targeted mutation 1.1, Hsin-Fang Yang-Yen
MGI:5521597
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gata1tm1.1Yen/Gata1tm1.1Yen involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5521636
cx2
 		Cdkn1atm1Tyj/Cdkn1atm1Tyj
Gata1tm1.1Yen/Gata1tm1.1Yen 		involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * FVB/N MGI:5522831
cx3
 		Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Gata1tm1.1Yen/Gata1tm1.1Yen 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5521638


Genotype
MGI:5521636
hm1
Allelic
Composition		 Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:200716 )
N
• mice exhibit normal peripheral blood composition
abnormal erythropoiesis ( J:200716 )
• erythrocyte-committed progenitors exhibit better survival in the absence of erythropoietin compared with wild-type cells
decreased erythroid progenitor cell number ( J:200716 )
• colony forming erythroid cells in the bone marrow




Genotype
MGI:5522831
cx2
Allelic
Composition		 Cdkn1atm1Tyj/Cdkn1atm1Tyj
Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1atm1Tyj mutation (3 available); any Cdkn1a mutation (63 available)
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:200716 )
N
• the number of colony forming erythroid cells is rescued




Genotype
MGI:5521638
cx3
Allelic
Composition		 Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l11tm1.1Ast mutation (4 available); any Bcl2l11 mutation (36 available)
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased erythroid progenitor cell number ( J:200716 )
• colony forming erythroid cells in the bone marrow




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory