About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(KRT14-FLT4/IGHG1)#Ali
transgene insertion, Kari Alitalo
MGI:5522572
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(KRT14-FLT4/IGHG1)#Ali/0 either: (involves: FVB/N) or (involves: BALB/c * DBA) MGI:5522642


Genotype
MGI:5522642
tg1
Allelic
Composition
Tg(KRT14-FLT4/IGHG1)#Ali/0
Genetic
Background
either: (involves: FVB/N) or (involves: BALB/c * DBA)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(KRT14-FLT4/IGHG1)#Ali mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Increase in mononuclear phagocyte system cells in Tg(KRT14-FLT4/IGHG1)#Ali/0 mice fed a low-salt diet

homeostasis/metabolism
• mice fed a high salt diet exhibit a 2-fold increase in chloride ion content in the skin compared with control mice
• mice fed a high salt diet exhibit a 1.5-fold increase in sodium ion content in the skin compared with control mice

immune system
• increased mononuclear phagocyte system (MPS) cells in mice fed a low salt diet
• mice fed a high or low salt diet fail to exhibit an increase in lymphatic capillary density unlike control mice

cardiovascular system
• in mice fed a high salt diet

hematopoietic system
• increased mononuclear phagocyte system (MPS) cells in mice fed a low salt diet





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory