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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(KRT14-FLT4/IGHG1)#Ali
transgene insertion, Kari Alitalo
MGI:5522572
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(KRT14-FLT4/IGHG1)#Ali/0 either: (involves: FVB/N) or (involves: BALB/c * DBA) MGI:5522642


Genotype
MGI:5522642
tg1
Allelic
Composition
Tg(KRT14-FLT4/IGHG1)#Ali/0
Genetic
Background
either: (involves: FVB/N) or (involves: BALB/c * DBA)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(KRT14-FLT4/IGHG1)#Ali mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Increase in mononuclear phagocyte system cells in Tg(KRT14-FLT4/IGHG1)#Ali/0 mice fed a low-salt diet

homeostasis/metabolism
• mice fed a high salt diet exhibit a 2-fold increase in chloride ion content in the skin compared with control mice
• mice fed a high salt diet exhibit a 1.5-fold increase in sodium ion content in the skin compared with control mice

immune system
• increased mononuclear phagocyte system (MPS) cells in mice fed a low salt diet
• mice fed a high or low salt diet fail to exhibit an increase in lymphatic capillary density unlike control mice

cardiovascular system
• in mice fed a high salt diet

hematopoietic system
• increased mononuclear phagocyte system (MPS) cells in mice fed a low salt diet





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory